10 April 2026

The New Scientist has produced an interesting collection of articles on ‘How to Think about the Human Mind’.  One of the most extraordinary chapters introduces us to the placebo effect.  Luana Colloca is a neuroscientist and says, ‘We must harness the placebo response to treat anxiety and pain.’

Whilst doing some research on people suffering from Parkinson’s, patients had been given the injection of a placebo which they believed was the real drug. ‘Despite this having no active ingredient, their rigidity somehow unlocked or the tremor decreased, and they reported feeling better.’ she said.

In addition, changes could be detected in the brain. ‘Through the electrodes (implanted in the brain), you could see a change in the neuronal activity along with the motor changes.’ A positive mindset that what is being given will work is helpful.

One of the areas of research included determining whether the placebo effect can help to control pain. This would have the advantage of ensuring that people didn’t become addicted to opioids. Research has shown that catastrophizing our predicament works against us.

Thoughts such as, ‘There is nothing I can do to reduce the intensity of my pain.’ Or ‘It’s never going to get any better.’ not only reduces the placebo effect but actually amplifies the distress caused. Self-control is an effective check on this way forward.

There is a genetic component to the success of the placebo effect. Some people are more favourably disposed to it. But research has shown that ‘people who have experienced trauma in early life show a smaller placebo effect’.  Jesus knew all about securing our well-being by embracing childhood. ‘Suffer the little children to come unto me…’